Professors


Professor Xianting Ding


Dr. Xianting Ding is the Executive Deputy Director of Insititue for Personalized Medicine (IPM) and professor at School of Biomedical Engineering, Shanghai Jiao Tong University. He received his Ph.D. degree from Department of Mechanical Engineering at University of California, Los Angeles (UCLA) in 2012. His research interests focus on developing Personalized Therapy and Precision Medicine, including: 1) developing bio-sensors for early detection of cancer, infectious disease, metabolic diseases, age-related diseases, cardiovascular diseases, based on cellular electrochemical, impedance, mechanical and photonic signaling; 2) developing personalized treatment; optimizing drug combinations; studying drug-drug interactions; building up models for bio-complex systems, based on Feedback System Control (FSC), Microfluidics and Bio-MEMS; 3) Traditional Chinese Medicine (TCM) modernization, extraction, purification, and re-combination for treating ischemia, osteoporosis and depression.
He participated in the early investigation and development for 3 international research centers, including Institute for Cell Mimetic Space Exploration (CMISE, funded by NASA), Center for Cell Control (CCC, funded by NIH) and Institute for Personalized Medicine (IPM, funded by Chinese Central Organization Department). He is now leading 16 combinatorial-drug-optimization related international projects. He is the editorial board member for Scientific Reports and Journal of the Association for Laboratory Automation (JALA), the reviewer for 7 journals, published 50 peer reviewed journal papers and filed 20 national or international patents.
Research Interests: Personalized medicine; Drug Combination Optimization; Bio-sensors; Microfluidics; CyTOF

 

丁显廷,中国中组部“青年千人”计划获得者;香港求是基金会“求是杰出青年奖”获得者;美国南加州中华科学家工程师协会“青年科学家”奖获得者;上海市科协“飞翔计划”获得者。目前担任美国比尔.盖茨基金会(Bill & Melinda Gates Foundation)“肺结核和艾滋病组合药物的临床研发”专项,中国负责人;中国科技部十二五“重大新药创制专项”,项目负责人;军委科技委国防创新特区第一批启动项目,课题负责人;中国科技部“国家重点研发计划”前沿和共性技术创新,课题负责人;中国卫计委“艾滋病和病毒性肝炎等重大传染病防治”重大科技专项,课题负责人;国家自然基金项目负责人;上海市科技创新行动项目负责人。美国加州大学洛杉矶分校(UCLA)博士学位,目前任上海交通大学特别研究员,与美国工程院院士、美国科学促进会(AAAS)院士、台湾中央研究院院士、中组部“顶尖千人计划”获得者、美国UCLA前科研副校长何志明(Chih-Ming Ho)院士共同创建上海交通大学个性化医学研究院,并担任研究院常务副院长。丁显廷博士参与过3个国际大型科研中心的建立:美国国家航空航天局(NASA)资助成立的Institute for Cell Mimetic Space Exploration (CMISE);美国国立卫生研究院(NIH)资助成立的Center for Cell Control(CCC);中国教育部和财政部资助成立的上海交通大学Institute for Personalized Medicine (IPM)。丁显廷博士是10个国际SCI期刊审稿人,2个国际SCI期刊的编委会成员,已发表包括Nature Communications, PNAS, Nature Protocols, Biosensors and Bioelectronics, Scientific Reports在内的国际SCI论文50余篇,申请发明专利30余项。目前还担任上海市免疫学会免疫遗传专业委员会,常务委员;上海市药学会药物治疗专业委员会,委员;上海医学会神经免疫学会,委员;国防创新特区技术组,专家委员;全国卫生产业协会实验医学专家委员会青年委员会,委员等社会学术团体职务。曾经或正在负责14个国际合作项目(合作研究所包括美国、日本、瑞士、意大利、台湾、香港等)。
科研方向主要集中在个体化诊断、医疗相关的研究:1)多靶标诊断,通过生物工程手段,如微纳米流体(Microfluidics)、质谱流式技术(CyTOF)、生物电化学技术(bio-electrochemical)等,对癌症、传染病、代谢病等重大疾病开展多靶标的个体化早期诊断;2)多靶标医疗,通过工程反馈系统控制技术(Feedback System Control)、计算生物学(Computational Biology)等手段,研究多药物组合(包括中药和西药)与生物复杂系统间相互作用;3)多靶点中药现代化:对中药药材和中药古方中有效部位和有效单体进行提取、纯化、再复方,用于治疗包括缺血、骨质疏松、抑郁症和帕金森综合症等疾病。
研究方向:多靶点疾病早期诊断、药物组合优化、生物信息检测与传感、生物复杂性分析与建模、生物微流控芯片开发

 


Professor Chih-Ming Ho

Dr. Chih-Ming Ho holds the Ben Rich-Lockheed Martin Professor in UCLA School of Engineering. After receiving his Ph.D. from The Johns Hopkins University, Dr. Ho started his career at the University of Southern California and rose to the rank of Full Professor. In 1991, he moved to the University of California, Los Angeles to lead the establishment of the micro-electro-mechanical-system (MEMS) field in UCLA and served as the founding Director of the Center for Micro Systems. To this day, the UCLA MEMS research has been recognized as one of the top three programs in the world. He is the Director of NIH supported Center for Cell Control (CCC) and was the Director of NASA supported Institute for Cell Mimetic Space Exploration (CMISE). He served as UCLA Associate Vice Chancellor for Research from 2001 to 2005.
He is known for his contributions in bio-nano technology, micro/nano fluidics, and turbulence. He was ranked by ISI as one of the top 250 most cited researchers in all engineering category around the world. In 1997, Dr. Ho was inducted as a member of the National Academy of Engineering. In the next year, he was elected as a fellow of American Association for the Advancement of Science. Dr. Ho holds seven honorary professorships. He has published 300 papers and 10 patents. He presented over 150 keynote talks in international conferences. Dr. Ho was elected Fellow of the American Physical Society as well as American Institute of Aeronautics and Astronautics for his contributions in a wide spectrum of technical areas.
In addition to his academic accomplishments, he has made extensive contributions to the professional societies around the world. He has chaired the Division of Fluid Dynamics (DFD) in American Physical Society, which is the leading platform in the United States for scientists interested in fundamental fluid dynamics. He was on the advisory board for AIAA Journal. He is a member of the IEEE/ASME JMEMS coordinating Committee. He was an Associate Editor of the ASME Journal of Fluids Engineering and an Associate Editor of the AIAA Journal. He also has served as a Guest Editor for Annual Review of Fluid Dynamics.
On the international level, he has served on advisory panels to provide assistance to many countries and regions, China, France, Hong Kong, Israel, Japan, Korea, Switzerland, Taiwan, Thailand, and United Kingdom on the developments of nano/micro technologies. Dr. Ho also has chaired or served on numerous organizing committees of international conferences on high technology topics.

何志明教授,美国国家工程院院士、美国科学促进会(AAAS)院士、中国台湾中央研究院院士、原美国加州大学洛杉矶分校(UCLA)副校长、美国物理学会和美国航空航天协会资深会员(Fellow)、UCLA班黎奇-洛克西德马丁奖座教授(Ben Rich - Lockheed Martin professor)、UCLA工学院细胞控制中心(Center for Cell Control)主任、UCLA细胞仿生探索(Cell Mimetic Space Exploration)研究所所长。目前担任上海交通大学个性化医学研究院院长、南京大学校长特别顾问、北京大学工学院顾问委员会主席。何教授拥有7个荣誉讲座教授,在微流体力学、生医微机电系统、纳米生物科技、微流体生医系统、微/纳米应用流体学、紊流等研究领域作出了开创性的贡献,被ISI列入全世界工程领域250位论文最常被引用研究者之一。
何教授是国际知名的微机电领域及纳米科技大师。1967年自台湾大学机械系毕业后,随即赴美深造,1974年于美国约翰霍普金斯大学获得力学博士学位后,任教南加州大学航空工程学系。1992年转至加州大学洛杉矶分校机械航空工程学系任教至今。在微流体力学,生医微机电系统,纳米生物科技,微流体生医系统、微/纳米应用流体学、紊流等研究领域作出了开创性的贡献。何院士1997年以其在流体科学之原创性成就获选美国工程科学院院士。次年又当选为中央研究院第二十二届数理组院士。对于紊流系统之了解与控制,以及使用微转换器于航天科学具有突破性之贡献。何教授亦曾为美国物理协会、美国航天空协会等推选为院士会员。何教授2004年荣获成功大学李国鼎讲座教授,拥有7个荣誉讲座教授,并曾为许多著名国际重要学会理监事和著名期刊之编辑委员。由于在科技领域中广泛杰出的贡献,何教授博士的研究生涯致力于不断探索和发现科学新疆界, 而成为横跨紊流系统,微纳米流体科学和生物纳米科技研究领域中享誉世界的科学家。何教授发表超过250篇国际期刊论文、获得10项专利并担任超过100场国际研讨会之keynote主讲人,期刊论文被ISI列入全世界工程领域250位最常引用研究者之一,学术成就备受各界推崇。

AWARDS

Member: National Academy of Engineering
Citation: For contributions to the understanding and control of turbulent flows.
Member: Academia Sinica
Fellow: American Institute of Aeronautics and Astronautics
Citation: For seminal contributions to the basic understanding and control of turbulent shear flows and for pioneering contributions to applying microtransducers to aerospace science.
Fellow: American Physical Society
Citation: For contributions in understanding the sensitivity of free shear layers under perturbations or geometrical variations in initial conditions. His pioneering works have been served as bases for controlling the evolutions of turbulent free shear layers.

PATENTS

“Optical Pressure Transducer Randomly Distributed Fiber Optics,” United States Patent Number 4,158,310. Issued: June 19, 1979.
“Mixing Apparatus Using a Noncircular Jet of Small Aspect Ratio,” United States Patent Number 4,519,423. Issued: May 28, 1985.
“Electromagnetically Actuated Micromachined Flap,” United States Patent Number 5,629,918. Issued: May 13, 1997.
“Micromachined Hot-Wire Shear Stress Sensor,” U.S. Patent 5,883,310. Issued: March 16, 1999.
“A Method for Aligning and Forming Microelectromechanical Systems (MEMS) on Contouring Surfaces,” U.S. Patent 5,905,007, March 18, 1999. (CM Ho and WJ Li)
“Flexible Skin Incorporating MEMS Technology,” U.S. Patent 6,071,819. Issued June 6, 2000
“Apparatus and Method for Using Bubble as Virtual Valve in Microinjector to Eject Fluid,” U.S. Patent 6,102,530. Issued August 15, 2000
“Electronics Integrated with Bio-Reactor/Channel for Detection or Fabrication of Bio-Materials,” Patent Pending
“Electrochemical Detection of Mismatch in Nucleic Acids (EDEMNA),” Patent Pending
“Ultrasensitive Molecular Detection of Urinary Pathogens,” Patent Pending
“Micro-Chaotic Mixer,” U.S. Patent Number 6,902,313, 06/17/2005
“Control Devices for Evaporative Chemical Mixing/Reaction,” Patent Pending